Built Without Bacteria: Bringing Cell-Free Synthesis to the Bench

Complex DNA workflows are often slowed by bacterial cloning, challenging genome sequences, and lengthy production cycles. A technology that brings cell-free DNA synthesis directly to the bench would give researchers an accessible, on-demand way to build high-fidelity DNA sequences without bacteria. Such an approach is now offered by Ribbon Bio’s MiroMine^TM: this helps avoid bacterial contaminants such as endotoxins and host-cell DNA, while supporting complex or sensitive sequences that can be difficult to produce through conventional cloning.

In this GEN webinar, speakers from Flock Bio and Ribbon Bio will explore how bench-based, cell-free DNA production can complement expertise in custom DNA design and manufacturing. Drawing on applications including CRISPR screening, enzyme evolution, lineage tracing, and massively parallel reporter assays (MPRAs), they will discuss how MiroMine^TM can reduce dependence on conventional cloning, shorten production cycles, and give researchers greater control and confidentiality. Attendees will learn how accessible cell-free synthesis can accelerate the path from design to experiment and enable cleaner, faster, and more flexible research workflows.

A live Q&A session will follow the presentations, offering you a chance to pose questions to our expert panelists.

Produced with support from: