Expert Perspectives on the COMBINE Angina Study - with Dr Hanish Gupta

In this video, Dr. Hanish Gupta, Senior Consultant Physician and Cardiologist, Life Aid Clinic, New Delhi, shares his clinical insights as an investigator in the COMBINE Angina Study presented at ESC Congress 2025. The study evaluated the early addition of a metabolic modulator in patients with stable angina who remained symptomatic despite first-line hemodynamic therapy. In this conversation, Dr. Gupta discusses the following questions:

1. What Motivated you to participate in the COMBINE- Angina Study as an Investigator?

2. How does this early combination weigh clinically?

3. Is SAQ-7 a commonly used tool in practice?

4. In real life how does improvement in SAQ-7 score actually translate for your patients and how actually do these changes show up into the daily day-to-day lives?

5. Can these results be extrapolated to Indian patients?

6. As an Investigator of the COMBINE-Angina study, what is one practical clinical message you’d like to share with your Indian colleagues?

Watch the full video for expert perspectives on stable angina management and evolving clinical approaches.